QuantiFERON - TB

QuantiFERON -TB Gold Plus QFT -Plus ELISA bipacksedel

Nil (IU/ml) TB1 minus Nil (IU/ml) TB2 minus Nil (IU/ml) Mitogen minus Nil (IU/ml) QFT -Plus Result Re sult interpretation ≤8.0 ≥0.35 and ≥25% of Nil Any Any Positive M. tuberculosis infection likely Any ≥0.35 and ≥ 25% of Nil <0.35 or ≥0.35 and <25% of Nil <0.35 or ≥0.35 and <25% of Nil 1. NIL (grå kork) negativ kontroll 2. TB1 antigen (grön kork) 3. TB2 antigen (gul kork) 4. Mitogen (lila kork) positiv kontroll.

n tested. A low response to mitogen (<0.5 IU/mL) indicates an Indeterminate result when a blood sample also has a 200 QFT-Plus HA Blood Collection Tubes (50 each: Nil, TB1, TB2 and Mitogen tubes) QFT-Plus is an in vitro diagnostic aid for detection of Mycobacterium tuberculosis infection. QFT-Plus is an indirect test for M. tuberculosis infection (including disease) and is intended for use in conjunction with risk assessment, radiography, and other medical and diagnostic evaluations. The MITOGEN-NIL value serves as the positive control for the patient specimen, demonstrating successful lymphocyte activity. The TB1-NIL tube specifically detects CD4+ lymphocyte reactivity, specifically stimulated by the TB1 antigens. The TB2-NIL tube detects both CD4+ and CD8+ lymphocyte reactivity, stimulated by TB2 antigens.

QFT-Plus is an indirect test for M. tuberculosis infection (including disease) and is intended for use in conjunction with risk assessment, radiography, and other medical and diagnostic evaluations. NIL 0.01 IU/mL MITOGEN-NIL >10.00 IU/mL TB1-NIL 0.00 IU/mL TB2-NIL 0.01 IU/mL The Nil tube value reflects the background interferon gamma immune response of the patient's blood sample. This value has been subtracted from the patient's displayed TB and Mitogen results.

IGRA-tester - Infektionssjukdomar och vaccinationer - THL

Kontrollera att blodet når Mätvärde för både TB1-NIL och TB2-NIL och ett sammanfattande resultat Mitogen Control (stimuleringskontroll) med lila kork – märk med lila etikett (se nedan). Om både TB1-NIL och TB2-NIL-resultaten är <0,35 IU/ml (och NIL och Mitogen kontroller uppfyller kvalitetskraven) Positiv Om något eller både Två innehåller M. tuberculosis-specifika peptidantigener (TB1 TB2), ett innehåller kontrollmitogen (Mitogen) och ett innehåller inga stimulanter (Nil). Laboratoriet betraktar resultatet av IGRA-testet som positivt om resultatet av TB1 eller TB2 är rör 1 (TB1) och TB antigen rör 2 (TB2).

Tuberkulos IGRA - Webbsortiment

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NIL (grå kork) negativ kontroll 2. TB1 antigen (grön kork) 3. TB2 antigen (gul kork) 4. Mitogen (lila kork) positiv kontroll. Direkt efter provtagningen. Skaka rören för hand. Håll rören med korken uppåt.
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QFT-Plus を用いた測定判定基準（下表は海外における判定基準と同一） Nil 値（IU/mL） TB1 値（IU/mL） TB2 値（IU/mL） Mitogen値（IU/mL）* 結果解釈 8.0 以下 0.35以上かつ tb1，tb2からそれぞれ陰性コントール値を引いた tb1値，tb2値のどちらかカットオフ値以上ならば原則陽性である。また，判定不可は陰性コントール値（nil値）の高値によっても判定不可となることなどが追加された。いずれも世界と同じ判定基準となった。 Ensure proper use and accurate results of QuantiFERON®-TB Plus, the latest in tuberculosis (TB) blood testing.

Two of the 4 collection tubes contain antigens representing certain Mycobacterium tuberculosis proteins and 2 of the tubes are controls (Nil and mitogen). TB Antigen Tube 1 (TB1) and TB Antigen Tube 2 (TB2) both contain peptide antigens from the Mycobacterium tuberculosis (MTB)-complex-associated antigens ESAT-6 and CFP-10 and are designed to elicit a cell-mediated immunity (CMI) response from CD4+ T-helper lymphocytes.
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QuantiFERON -TB Gold Plus QFT -Plus ELISA bipacksedel

Quantiferon -tB gold Plus (Qft -Plus) QuantiFERON®-TB Gold Plus (QFT®-Plus) Blood Collection Tubes 1 Blood Collection 17–25°C (Cat.no: 622222) For use between sea-level and 810 m (2650 ft) Contents Mitogen TB2 TB1 Nil Use outside the specified altitude range may result in a change to the blood draw volume. • All indeterminate – low mitogen (most cases) or nil > 8 IU/ml(most cases) or nil > 8 IU/ml • Negative result with high nil • Negative result when the (TB Ag – nil) value = 0.25 to 0.35 • All positive results **(If two results are discordant, the sample is duplicated the next Positive results by TB1, TB2, or both are considered positive. See the table below.1 Interpretation of QFT-Plus results Nil TB1 minus Nil (IU/ml) TB2 minus Nil (IU/ml) Mitogen minus Nil (IU/ml) QFT-Plus result Report/Interpretation < 8.0 ≥0.35 and ≥25% of Nil Any Any Positive M. tuberculosis infection likely Any <0.35 or ≥0.35 and The QFT-Plus assay has 2 distinct TB antigen tubes: TB Antigen Tube 1 (TB1) and TB Antigen Tube 2 (TB2). Both tubes contain peptide antigens from ESAT-6 and CFP-10 for stimulation of a CD4+ T-cell IFN-gamma response.

Lower than expected results with the Mitogen tube Taking it step by step, first evaluate the Nil and the mitogen result and then the results of the TB1 and TB2. Significance of the NIL result : The NIL indicates the presence of any residual interferon-γ found in the patient’s blood due to an infection with an organism requiring cell mediated immunity/T cell immunity (e.g. virus, fungus, intracellular bacteria, etc.). Nil (grey cap), TB1 antigen (green cap), TB2 antigen (yellow cap) Mitogen (purple cap) Tb-Quantiferon Gold specific tube sets: How to obtain tubes for customers both inside and outside the Auckland region Internal Contact Lablink x22000 Lablink is staffed for these requests Monday - Friday: 8am - 3.30pm Note: QFT-Plus has 4 blood collection tubes: Nil, TB1, TB2, and Mitogen. Collect 1 ml of whole blood into each tube. Incubate for 16 to 24 hours at 37°C. Detect released IFNγ in harvested plasma by ELISA.